https://www.proz.com/kudoz/english-to-polish/medical-general/6273173-btk-occupancy-samples.html
Feb 8, 2017 20:02
7 yrs ago
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English term

BTK Occupancy samples

English to Polish Medical Medical (general) clinical studies
If the site is capable to provide BTKO samples, the following question will be asked:
Will BTK Occupancy samples be collected from this subject?

Badanie kliniczne dotyczy stwardnienia rozsianego. Przypuszczam, że BTK oznacza "Bruton's tyrosine kinase", ale potrzebuję fachowego tłumaczenia dla całego terminu.

Proposed translations

+1
5 hrs
Selected

próbki do pomiaru stopnia wysycenia BTK

IMO chodzi o stopień wysycenia/związania BTK przez dany lek.
Example sentence:

Using a fluorescently tagged derivative of ibrutinib, PCI-33380, it was shown that 10 nM of ibrutinib was sufficient to achieve full BTK occupancy and completely prevent upregulation of CD69, a surrogate for B-cell activation, in primary B-cell cultures.

Peer comment(s):

agree Frank Szmulowicz, Ph. D.
10 mins
Dziękuję :-)
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4 KudoZ points awarded for this answer. Comment: "Dziękuję."