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Glossary entry

Spanish term or phrase:

síndrome de impregnación

English translation:

constitutional symptoms

Added to glossary by Angelo Berbotto
Dec 9, 2021 01:07
2 yrs ago
25 viewers *
Spanish term

síndrome de impregnación

Spanish to English Medical Medical (general)
En un paciente que van a internar para hacer una descompresión de la vía biliar y tiene síndrome coledociano y "síndrome de impregnación"
Proposed translations (English)
4 +1 constitutional symptoms
3 maximum tolerated dose
2 saturated fats metabolic syndrome

Discussion

neilmac Dec 11, 2021:
FWIW When I first saw the query, I thought it might mean false pregnancy syndrome, but apparently that's "Embarazo psicológico".

Proposed translations

+1
40 mins
Selected

constitutional symptoms

"Síndrome de impregnación" is a rather old-fashioned and poorly defined term for what are usually referred to in English as "constitutional symptoms"—typically weakness/fatigue, involuntary weight loss, and anorexia (sometimes low-grade fever). It is often indicative of cancer or other wasting diseases, such as tuberculosis. Depending on the country, it may also be called "síndrome de repercusión general" or simply "repercusión general".

This is a fascinating (to me), almost culture-specific concept, and I don't think it is recognized as a pathological entity in its own right in any formal system (ICD, etc.).

Also worth noting that "síndrome coledociano" is *not* a "choledochal syndrome", but rather Charcot's triad.

Suerte :)
Peer comment(s):
neutral philgoddard : Maybe, but you haven't given any references.
5 hrs
Fair enough! I don't think I *can* find any references showing head-to-head equivalence of the two, though—this is an extremely country-specific term.
agree liz askew
9 hrs
Thanks, Liz!
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4 KudoZ points awarded for this answer. Comment: "thank you - this is the most persuasive answer. Thanks to everyone who took the time to answer."
31 mins

maximum tolerated dose

The highest dose of a drug or treatment that does not cause unacceptable side effects. The maximum tolerated dose is determined in clinical trials by testing increasing doses on different groups of people until the highest dose with acceptable side effects is found. Also called MTD.

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Note added at 33 mins (2021-12-09 01:41:02 GMT)
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https://www.cancer.gov/publications/dictionaries/cancer-term...


https://www3.paho.org/relacsis/index.php/en/foros-relacsis/f...

Síndrome de impregnación en medicina: “Se llama así al tope de las dosis terapéuticas de un medicamento o tratamiento que un paciente puede recibir sin causarle efectos secundarios inaceptables, que son necesarias para lograr el efecto buscado rápidamente”3.

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Note added at 1 hr (2021-12-09 02:19:42 GMT)
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New term to me, the other answer is good, the same article above agrees with the other possible answer....quote • El Síndrome de impregnación consiste en malestar general, cansancio, y apatía, pudiéndose presentar además cefalea, mialgias y odinofagia.1

• El Síndrome de impregnación puede presentarse en diferentes patologías como por ejemplo: Tuberculosis Pulmonar (Síndrome de impregnación bacilar)

2, también en diversos tumores malignos (Síndrome de impregnación en oncología).
Example sentence:

Maximum tolerated dose is the the pont of saturation.

Reference:

https://www.cancer.gov/publications/dictionaries/cancer-terms/def/maximum-tolerated-dose

https://www3.paho.org/relacsis/index.php/en/foros-relacsis/foro-becker-fci-oms/respuestas-foro-becker/61-foros/consultas-becker/953-sindrome

Peer comment(s):
neutral philgoddard : I've looked at your paho.org reference, but it doesn't make sense to me and I wonder if it's some kind of mistake. I don't see any connection between a syndrome and a dose.
5 hrs
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3 days 17 hrs

saturated fats metabolic syndrome

If this is about gallstones, as in 'síndrome coledociano' and cholecystectomy: then - pace Phil G. - 'descompresión de la vía biliar .. ' in the string starting with the biliary tract suggests a congruous alternative in the context.
Example sentence:

saturated fatty acids; metabolic syndrome; diet quality; dietary guidelines; cardiovascular disease.

Current dietary guidelines discourage the consumption of saturated fat and dietary sources rich in saturated fat

Reference:

http://www.healthline.com/nutrition/saturated-fat

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