English to Russian Medical Medical (general)

With continued exposure or repeated cycles, the receptor downregulation causes the glands to lose their sensitivity to estrogens and progestins, leading to progressively less secretory change (‘secretory exhaustion’), such that they ultimately appear atrophic. At this stage, which only occurs after prolonged exposure or multiple cycles, the appearance is that of decidualized stroma with widely dispersed atrophic glands, often referred to as a *‘pill’ endometrium*. More slowly, the decidualized stroma also begins to be suppressed by the receptor downregulation, and over months to years will become attenuated and atrophic, ultimately losing most of its decidual features. At this point, the appearance resembles endometrial atrophy due to menopause or hormone suppression.