would be a good choice.

itre du document / Document title
Cognitive brain function in non-demented patients with ** low-grade and high-grade carotid ** artery stenosis
Auteur(s) / Author(s)
MADL C. (1) ; GRIMM G. (1) ; KRAMER L. (1) ; KOPPENSTEINER R. ; HIRSCHL M. ; YEGANEHFAR W. (1) ; HIRSCHL M. M. (1) ; UGURLUOGLU A. ; SCHNEIDER R. ; EHRINGER H. ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Univ. Vienna, dep. medicine IV, 1090 Vienna, AUTRICHE


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http://cat.inist.fr/?aModele=afficheN&cpsidt=4216650

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http://www.ingentaconnect.com/content/tandf/scar/2006/000000...

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Results. Early mortality was 1.9% and 2.3%, respectively, if there was no or a ** low-grade LMCA stenosis ** vs. 6.3% if the stenosis was high-grade. Ten-year survival was 76% if no LMCA obstruction, 74% if low-grade stenosis and 64% if the stenosis...

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http://stroke.ahajournals.org/cgi/content/full/36/11/2337

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Carotid stenosis of a severity that warrants surgical or endovascular treatment is found in 10 to 20% of all patients with transient ischemic attack (TIA) or ischemic stroke. Atrial fibrillation occurs in 5% to 10% of these patients and small vessel disease in 25%. In the remaining patients, moderate carotid atherosclerosis with ** low-grade stenosis ** is probably an important causative prognostic factor, but this has not been systematically studied. Indeed, prediction of recurrent stroke lacks precision, probably because we lack simple, reliable, and valid indicators of moderate carotid atherosclerosis.3,4 Noninvasive analysis of plaque morphology could fill this gap.

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http://ahavj.ahajournals.org/cgi/content/full/strokeaha;01.S...

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** Low-Grade Carotid Stenosis **

Looking Beyond the Lumen With MRI

Bruce A. Wasserman, MD, Robert J. Wityk, MD, Hugh H. Trout, III, MD and Renu Virmani, MD
From the Russell H. Morgan Department of Radiology and Radiological Sciences (B.A.W.) and the Department of Neurology (R.J.W.), The Johns Hopkins Hospital, Baltimore, Md; the Department of Surgery (H.H.T.), Suburban Hospital, Bethesda, Md; and CVPath (R.V.), International Registry of Pathology, Gaithersburg, Md.

Correspondence: Correspondence to Bruce A. Wasserman, MD, The Russell H. Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins Hospital, Phipps B-100, 600 N Wolfe St, Baltimore, MD 21287. E-mail [email protected]


Abstract
TOP
Abstract
Introduction
The Need to Look...
Uncovering Plaque Size and...
Plaque Progression Through...
Plaque Assessment by MRI
High-Resolution MRI for...
Limitations of MRI for...
When to Image Low-Grade...
Implications of High-Resolution...
Summary
References

Background and Purpose— The management of carotid atherosclerosis is well-established for symptomatic stenosis above 69%, but the optimal approach for managing lower degrees of narrowing remains uncertain. Because the risk of stroke increases with higher grades of stenosis, we are inclined to consider low-grade disease to be low risk. This approach, however, does not take into account other factors such as plaque size or composition. Plaque may progress to a substantial size before it demonstrates significant stenosis by angiography. We know that low-grade disease can result in cerebrovascular ischemic events, but predicting vulnerable lesions has not been possible by relying on stenosis alone.