English to German Science Genetics

The double-stranded duplexes are treated with an agent which cleaves single-stranded regions of the duplex such as which will exist due to basepair mismatches between the control and sample strands.

Ich kenne nur die Begriffe coding (oder sense) strand vs. template (oder antisense) strand. Sind "control & sample strands" Synonyme oder bedeuten sie etwas ganz Anderes?