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вокс
Sep 7, 2013 08:23
10 yrs ago
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Russian term

глыбчатая концентрация ядерного хроматина

Russian to English Medical Medical (general) глыбчатая концентрация ядерного хроматина
глыбчатая концентрация ядерного хроматина глыбчатая концентрация ядерного хроматина
Proposed translations (English)
5 +1 concentration of granular nucleic chromatin
4 blocklike concentration of nucleic chromatin
Change log

Sep 7, 2013 20:58: Alexander Konosov changed "Language pair" from "English to Russian" to "Russian to English"

Sep 7, 2013 20:59: Alexander Konosov changed "Language pair" from "Russian to English" to "English to Russian"

Sep 7, 2013 21:00: Alexander Konosov changed "Language pair" from "English to Russian" to "Russian to English"

Discussion

Jack slep Sep 9, 2013:
Oh my, you're talking about "concentration" in chemistry, medical and related fields. Concenration is also the result of concentrating, a concentrated mass of something, a concentrate, and it's used in other fields, with shape and dimensionless, e.g., circular stress concentration in metallurgy, or triangular, e.g.,

Air Pollutants and the Respiratory Tract
David Swift, ‎W. Michael Foster - 1999 - ‎Medical
... air (solid line, circles), 120 ppb steady-state concentration of 03 (short dashed line, squares), and triangular concentration of 03 (long dashed line, triangles).
[PDF]
Coleoptera: Cleridae: Enopliinae - Redalyc

www.redalyc.org/pdf/424/42409907.pdf‎

triangular concentration of asperities, remainder of surface with densely and deeply placed, moderate-size punctations; pubescence consisting of rather long ...
Phazaca unicaudoides - The Moths of Borneo
www.mothsofborneo.com/part-8/epipleminae/epipleminae_13_7.p...‎
The female has central, rather triangular concentration of setae to the valve. The female has narrow, rather acute ovipositor lobes, a conical ostium with the ...
Natalie Sep 9, 2013:
OK, thank you, Amy - I give up. Maybe it is correct in English, but in Russian it is definitely wrong.
Amy Lesiewicz Sep 9, 2013:
Concentration Concentration can also refer to a "clump" or "grouping" of something; see definition #3 here: http://dictionary.reference.com/browse/concentration?s=t
Natalie Sep 9, 2013:
:-((( In this case, dear Jack, I can only repeat: "concentration" is an amount of a substance per defined space; it is expressed in terms of mass per unit volume, and has no shape; it just cannot be round, elongated, right-angled, diamond-shaped, and it cannot be blocklike...
Jack slep Sep 9, 2013:
No, Natalie, I meant the product "концентрация" and not the process "концентрирование"; that is, chromatin is concentrated/condensed in the form of blocks. (Concentration and condensation can be synonomous in English but I doubt that is the case in Russian.) In any event, my friend, I bow to your far superior knowledge in this field. Actually, my real question was the translation of глыбчатая as granular, but I'm just used to other Russian terms for granular in medical fields.
Natalie Sep 9, 2013:
I think I have understood your point, Jack: you mean that "концентрация" is used here in the meaning of "концентрирование", i.e. the same process as condensing. In this case the source also is blatantly wrong, as it should read "глыбчатОЕ концентрИРОВАНИЕ ядерного хроматина", and, moreover, all the same this would be wrong from the scientific point of view (could be used as a kind of laboratory slang only)
Natalie Sep 9, 2013:
Jack, I don't object to blocks/blocklike etc., it is just one of a few synonyms used in this case. But I strongly object to applying "blocklike" to concentration: it is a blatant error in the source, and it is nonsense, actually, as concentration of whatever cannot be neither round, elongated, right-angled, diamond-shaped nor blocklike: the concentration is something that has no shape. At the same time please note that condensation of a material CAN be blocklike, it mans a process of forming blocks.
Jack slep Sep 9, 2013:
This is your field, Natalie, but using глыбчатая for granular and applying it to chromatin instead of concentration just doesn't seem right. If you object to blocks, blocklike, then глыб(чатая) could refer to clumps, clumpy
The Washington Manual of Surgical Pathology
books.google.com/books?isbn=0781765277

The aspirate contains a monotonous population of small lymphoid cells with round nuclear contours, characteristic checkerboardlike clumpy chromatin, and ...


www.ncbi.nlm.nih.gov/pubmed/3946301
The entity is characterized by a maturation arrest at the myelocyte stage, strikingly clumpy chromatin, and a clinical course marked primarily by difficulties caused ...

It is also stated that clumpy chromating changes to granular.
More statistics:
nucleic chromatin - 130
nuclear chromatin - 142,000

Just saying...
Natalie Sep 8, 2013:
A few statistics:
"chromatin blocks" - about 7,000 results
"chromatin masses" - about 27,900 results
"chromatin granules" - about 31,500 results

Moreover, "chromatin blocks" is used mostly in description of preparation staining (exactly like in Jack's examples).

"Blocks" is certainly not the correct term here.
Amy Lesiewicz Sep 8, 2013:
Thanks for the links, Jack. Always learning... :-)
Jack slep Sep 8, 2013:
amy, I'm more inclined to think it should have been "chromatin blocks" and not "masses":

Genes for embryo development are packaged in blocks of ...

genome.cshlp.org/content/21/4/578.full
The size and typical uniformity of these chromatin blocks strongly suggests a program for their establishment in the germline. Although the ...
Insulation of the Chicken β-Globin Chromosomal Domain from a ...

mcb.asm.org/content/23/18/6455.full

While in the quiescent MENT-expressing cells the H3me2K9 became notably concentrated at the Hoechst-positive chromatin blocks (Fig. 6, panels 3 and 4 and ...
Histone H3 variants specify modes of chromatin assembly


... domain suggests that origins have a fixed relationship to the chromatin blocks, and that H3-containing blocks replicate out of phase from Cid-containing blocks ...
Chromatin States Accurately Classify Cell Differentiation Stages
Amy Lesiewicz Sep 7, 2013:
See this recent KudoZ question as well :) http://www.proz.com/kudoz/russian_to_english/medical:_pharma...

Proposed translations

+1
28 mins

concentration of granular nucleic chromatin

It is chromatin that is granular, NOT concentration :-)

P.S. Sometimes you can encounter descriptional terms like "chromatin lumps", it is also correct, but "granular chromatin" is more universal.
Peer comment(s):
agree cyhul
1 day 18 hrs
Thank you!
Something went wrong...
1 day 7 hrs

blocklike concentration of nucleic chromatin

Since chromatin blocks is a common term as is block-like chromatin, it seems reasonable to assum that block-like (blocklike) concentration is a correct term.
Search Results. See below

“Chronic Lymphocytic Leukemia/Small Lymphocytic ...
www.cap.org/apps/docs/.../educational_activities_2012_bmd-a...‎
slightly larger and have more of a block-like (“cracked”) chromatin pattern. Reliable morphologic distinction between lymphoma cells of CLL/SLL and normal ...
block-like chromatin condensation - Search Engine for Medical ...
www.mtdictionary.com/block-like-chromatin-condensation/‎
Terms: Staring with: block-like, chromatin, condensation. Containing: block-like, chromatin, condensation. Ending With: block-like, chromatin, condensation ...
haliotis discus hannai - Current Zoology
www.currentzoology.org/paperdetail.asp?id=759‎
by LITWXU Ji-Lin - ‎Cited by 2 - ‎Related articles
The nucleus, round or curved shapes, is very electron dense in some sections, block-like chromatin scattered in the nucleus. The second cell type is excretory ...
Diagnostic Ultrastructural Pathology I: A Text-atlas of Case ...
books.google.com/books?isbn=0849344042
Ann M. Dvorak, ‎Rita A. Monahan-Earley - 1992 - ‎Medical
They displayed variable degrees of block-like chromatin condensation along the nuclear membrane. A few cells had large nucleoli. The nucleus was often ...

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Note added at 1 day7 hrs (2013-09-08 15:42:14 GMT)
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Other refs: Search Results

Cards: psycostimulants | Quizlet
quizlet.com/11817800/flashcards
... amphetamine in brain cocaine in brain chromatin cocaine and dna treatment for ... by blocking presynaptic dopamine transporter (reuptake block)-like cocaine.
Cell - Systematic Protein Location Mapping Reveals Five Principal ...
www.cell.com/abstract/S0092-8674(10)01057-3?switch=standard‎
Sep 30, 2010 - Finally, we provide evidence that the different chromatin types help to target DNA-binding factors to specific genomic regions. These results ...
Circulating ringed sideroblasts in the course of the initial erythremic ...
www.haematologica.org/content/81/4/376.full.pdf
by G Carulli - round nucleus, a delicate nuclear chromatin pattern, and one or two nucleoli. ... either diffuse or block-like positive material. (Figure 1b). Myeloperoxidase ...

These contained a red-brown stained nucleus with block-like aggregates of nuclear chromatin and abundant cytoplasm staining pale blue in some lymphocytes.
Bulletin of the Museum of Comparative Zoology at Harvard College

Harvard University. Museum of Comparative Zoology - 1907 - ‎Zoology
In the early growth period the chromatin largely loses its staining capaoity. Later the chromatin reasserts itself and appears in block-like masses of granules.

In the early growth period the chromatin largely loses its staining capacity. Later the chromatin reasserts itself and appears in block-like masses of granules.

Chronic Lymphocytic Leukemia—an Accumulative Disease of ...
bloodjournal.hematologylibrary.org/content/29/4/566.full.pdf‎
by W DAMESHEK - ‎1967 -
mature lymphocyte expands in size, its block-like chromatin nucleus becomes finer, nucleoli appear, the cytoplasm develops basophilia; that is, a transformation.

Wistar Institute of Anatomy and Biology - 1922 - ‎Biology
The block-like masses of chromatin of the preleptotene nuclei seem to become incorporated into a fine nuclear network which passes through a contraction ..
Peer comment(s):
neutral Natalie : Hi Jack, with all due respect: blocklike concentration is a nonsense! //Don't you feel the difference between "Blocklike concentration of chromatin" and "blocklike chromatin concentration"?
3 hrs
Hi Natalie, if you can have block-like chromatin condensation, www.mtdictionary.com why not concentration? Yes, I certainly recognize the difference: the concentration is blocklike in the first and the chromatin is blocklike in the second
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