English to Russian Medical Medical (general)

IN PATIENTS WITH RECURRENT CDI EPISODE(S), SHOULD FIDAXOMICIN BE USED RATHER THAN VANCOMYCIN?

In patients with recurrent CDI episodes, we suggest fidaxomicin (standard or extended-pulsed regimen) rather than a standard course of vancomycin (conditional recommendation, low certainty evidence).
Vancomycin in a *tapered* and pulsed regimen or vancomycin as a standard course are acceptable alternatives for a first CDI recurrence. For patients with multiple recurrences, vancomycin in a *tapered* and pulsed regimen, vancomycin followed by rifaximin, and fecal microbiota transplantation are options in addition to fidaxomicin.