Glossary entry (derived from question below)
English term or phrase:
bioavailability
Latvian translation:
bioloģiskā pieejamība
Nov 17, 2009 16:58
14 yrs ago
English term
bioavailability
GBK
English to Latvian
Medical
Medical: Pharmaceuticals
Definition from
USC Kidney Transplant Program:
a measure of how much of an administered drug is absorbed into the bloodstream, actually reaching the intended site of action in the body. For example, medicine is absorbed from the GI tract, travels through the bloodstream, and reaches the organ tissues, where it works to fight infection, prevent rejection, etc.
Example sentences:
Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential. (Merck & Co., Inc. )
The term “relative bioavailability” refers to a comparison of two or more dosage forms in terms of their relative rate and extent of absorption. If an intravenous injection is employed as the reference dose, one can determine the absolute bioavailability of the test dosage form. (Informa plc )
Drug candidates can be tested for their desired therapeutic activity, but it is not yet possible to predict whether or not a compound will have sufficient bioavailability to be useful and practical. (US National Institutes of Health)
Proposed translations
(Latvian)
| 5 +3 | bioloģiskā pieejamība |
Inese Poga-Smith
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Proposed translations
+3
1 day 21 hrs
Inese Poga-Smith
Canada
Canada
Canada
Perfect feeling of language performance
Native in: Latvian
Works in: Latvian to English, English to Latvian, German to Latvian
Related KudoZ points
:
87
Selected
bioloģiskā pieejamība
Ir iespējama arī saīsinātās formas "biopieejamība" lietošana, kaut gan oficiālos doku,entos un tulkojumos biežāk lietota pilnā forma "bioloģiskā pieejamība".
Definition from
Kopienas vērtējumprocedūra, Valsts va:
bioloģiskā pieejamība;bioavailability;biopieejamība bio-availability
Example sentences:
107. Farmakokinētikas pētījumos veic attiecīgus bioloģiskās pieejamības pētījumus, lai noteiktu bioekvivalenci šādos gadījumos: 107.1. no jauna formulētās veterinārās zāles salīdzina ar jau esošām zālēm; 107.2. jaunu ievadīšanas ceļu vai paņēmienu salīdzina ar jau esošo. 5. Ja saskaņā ar šo noteikumu 23.punktu bioloģiskas izcelsmes veterinārās zāles, kas ir līdzīgas bioloģiskas izcelsmes atsauces veterinārajām zālēm, neatbilst ģenērisko zāļu definīcijā minētajiem nosacījumiem, iesniedzējs iesniedz informāciju saskaņā ar šo noteikumu 2. vai 3.pielikuma 1. un 2.nodaļu (farmaceitiskie, ķīmiskie un bioloģiskie dati). Iesniedzamo informāciju papildina ar datiem par veterināro zāļu bioekvivalenci un biopieejamību, kā arī sniedz papildu datus, īpaši par veterināro zāļu drošumu un iedarbīgumu. (Cabinet Regulations, Republic of Latvia)
... bioloģiskās pieejamības un bioekvivalences pētījumi jāplāno un jāveic saskaņā ar Labas klīniskās prakses prasībām. (Medikamentu informācijas centrs)
English Translation: bioloģiskā pieejamība Language Expression English Translation or Definition Latvian bioloģiskā pieejamība bioavailability. Refers to that proportion of a drug which reaches the systemic circulation unchanged after a particular route of administration When drugs are taken by mouth their bioavailability is determined by factors in the drug-which include the nature of the molecule, its stability, and the formulation administered-and in the patient-such as a reduced intestinal surface area as a result of coeliac disease or intestinal resection and whether or not the drug is taken with a meal. Source: European Union. (references) (Webster's Online dictionary)
4 KudoZ points awarded for this answer.
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