socket

Spanish translation: "socket" (base de enchufe)

18:09 Dec 23, 2015

English to Spanish translations [PRO]
Science - Genetics / Genetics

English term or phrase: socket

Estoy traduciendo un estudio sobre hemofilia y encuentro esta palabra. No entiendo cuál es el significado específico en esta area ya que en otras sí lo tiene. El contexto serìa este.

Socket targeting construct. Socket/F9 (Fig 1) was constructed in the pPNT vector (a kind gift from Dr R.C. Mulligan, Massachusetts Institute of Technology, Cambridge, MA)16 using standard recombinant DNA techniques.17 It contains 5′ and 3′ homology regions of the factor IX gene, the socket, and a negative selection marker. The 1-kb 5′ homology region containing 5′ untranscribed sequences of the factor IX gene is followed by the socket, neoΔHPRT, which consists of the neo gene and a partially deleted, nonfunctional HPRT minigene. The neoΔHPRT genes are followed by the 5.5-kb 3′ homology region, which contains part of intron 3, exon 4, and part of intron 4. The negative selection marker, HSV-tk gene,16 is joined to the 3′ end.

Fernanda Cerretani KudoZ activity Questions: 1 (none open) Answers: 0 Argentina
Local time: 14:33

Spanish translation:"socket" (base de enchufe)

Explanation:
Se trata de un procedimiento de mutagénesis en el que primero se inserta el "socket" en el ADN de destino, para después insertar el "plug". No he visto nada en espanol al respecto, porque es un sistema reciente. Podrías dejarlo como "socket" con una aclaración.
Aquí se ve muy claro lo que es:
Plug and socket targeting... - Yale Image Finder
krauthammerlab.med.yale.edu/.../Figure.external?...
Fig. 1: Plug and socket targeting strategy for generation of F10 knockout and Friuli mice. (A) 'Socket' targeting construct consists of 2.8 kb 5′targeting arm and ..

Selected response from:

Teresa Mozo
Local time: 19:33

Grading comment

Muchas gracias!
4 KudoZ points were awarded for this answer

Summary of answers provided

"socket" (base de enchufe)

Teresa Mozo

Summary of reference entries provided

factor IX

José Patrício

Answers

15 hrs confidence:

"socket" (base de enchufe)

Teresa Mozo
Local time: 19:33
Specializes in field
Native speaker of:

Spanish
PRO pts in category: 69

Grading comment

Muchas gracias!

Reference comments

6 hrs

Reference: factor IX

Reference information:
factor IX gene, the socket - your question
provocada por la escasez de factor IX - http://www.linguee.es/espanol-ingles/search?source=auto&quer...

José Patrício
Portugal
Native speaker of:

Portuguese

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