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22:12 Jun 22, 2021 |
Italian to English translations [PRO] Medical - Medical: Instruments / CRRT | |||||||
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| Selected response from: texjax DDS PhD Local time: 06:02 | ||||||
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Summary of answers provided | ||||
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4 | citrate-calcium anticoagulation |
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citrate-calcium anticoagulation Explanation: Sebbene si trovino più occorrenze per calcium-citrate, l'elemento chelenate è il citrato per cui direi come sopra Strobl K, Hartmann J, Wallner M, Brandl M, Falkenhagen D: A target-oriented algorithm for citrate-calcium anticoagulation in clinical practice. Blood Purif 2013; 36: 136–145. Citrate just mixes with the blood before it enters the CRRT circuit as illustrated in the commonly used citrate-based CRRT regimens (Figures 1 to 3). Citrate chelates the ionised calcium, which is essential for the normal coagulation cascade and results in inhibition of thrombin generation. https://www.hkmj.org/abstracts/v21n2/149.htm Citrate is infused into the blood at the start of the extracorporeal circuit and provides anticoagulation by chelating ionized calcium (iCa++). For optimal anticoagulation, the citrate infusion is adjusted to blood flow. The target extracorporeal blood citrate concentration to inhibit coagulation is 4–6 mmol/l, corresponding to a pre-filter iCa++ concentration of |
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