Glossary entry (derived from question below)
Spanish term or phrase:
análisis del gen promotor del receptor X de pregnano
English translation:
analysis of pregnane X-Receptor gene promoter
Added to glossary by
Adam Burman
Oct 19, 2006 11:24
17 yrs ago
Spanish term
United Kingdom
análisis del gen promotor del receptor X de pregnano
Spanish to English
Medical
Medical (general)
Research report for new drug
En un análisis del gen promotor del receptor X de pregnano (PXR)/CYP3A4, a concentraciones de hasta 10 M, DVS-233 no indujo CYP3A4 humano.
TIA
TIA
Proposed translations
(English)
Proposed translations
+2
1 hr
Selected
analysis of pregnane X-Receptor gene promoter
see above refs in asker's box
Peer comment(s):
| agree |
raptisi
7 hrs
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| agree |
Maria Tsatsaroni
: I would just add "the" before pregnane. Otherwise, you're right on the button!
8 hrs
|
4 KudoZ points awarded for this answer.
Comment: "Great - thanks Liz. I think I've got my head round this one now!"
+2
7 mins
Ross Andrew Parker
Native in English
An eye for detail
Native in: English
Works in: Catalan to English, Spanish to English
Related KudoZ points
:
72
analysis of the gene promoter for the the pregnane X receptor
http://www.google.com/search?hl=en&lr=lang_en&as_qdr=all&q="...
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Note added at 9 mins (2006-10-19 11:33:14 GMT)
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an analysis of...
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Note added at 10 mins (2006-10-19 11:34:11 GMT)
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Should be "promoter"
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Note added at 13 mins (2006-10-19 11:37:45 GMT)
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Not "promotor"
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Note added at 9 mins (2006-10-19 11:33:14 GMT)
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an analysis of...
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Note added at 10 mins (2006-10-19 11:34:11 GMT)
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Should be "promoter"
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Note added at 13 mins (2006-10-19 11:37:45 GMT)
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Not "promotor"
Peer comment(s):
| agree |
Robert Copeland
0 min
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Thanks, robert.
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| agree |
Joost Elshoff (X)
: subtle differences :D, you were just ahead of me
6 mins
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Thanks, Joost.
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13 mins
analysis of the promoter gene for the Pregnane X Receptor (PXR)
Found some literature on this on the web about this...
hope it's useful!
hope it's useful!
-1
2 hrs
pregnane X receptor /CYP3A7 promoter gene analysis
my tuppence worth
it is not known if pregnane-x receptor has a promoter gene
it is not known if pregnane-x receptor has a promoter gene
Peer comment(s):
| disagree |
Maria Tsatsaroni
: You're right. It's not known if it has a promoter gene but it IS a gene promoter (promoting gene expression between species much like other xenobiotic receptors of monoxygenases (CYP3A) do). My objection is that it's a gene promoter,not a promoter gene
8 hrs
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Discussion
We have recently demonstrated that o,p’-DDT exposure increases CYP3A4 mRNA levels in HepG2 cells. To determine the mechanism by which o,p’-DDT induces CYP3A4 expression, transactivation and electrophoretic mobility shift assays were carried out reveling that o,p’-DDT activates the CYP3A4 gene promoter through the pregnane X receptor (PXR).
See:http://dmd.aspetjournals.org/cgi